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Why is this medication prescribed?

Phentermine is used, in combination with diet and exercise, to help you lose weight. It works by decreasing your appetite.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?

Phentermine comes in tablets and extended-release capsules. It usually is taken as a single daily dose in the morning or three times a day 30 minutes before meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phentermine exactly as directed.

Most people take the drug for 3-6 weeks; the length of treatment depends on how you respond to the medication. Phentermine can be habit-forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to.

To prevent side effects, phentermine should be taken with meals. If you are taking an extended-release (long-acting) product, do not chew or crush the tablet. There are some tablets that can be crushed and mixed with food.
What special precautions should I follow?

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Before taking phentermine,

* tell your doctor and pharmacist if you are allergic to phentermine or any other drugs.
* tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac), fluvoxamine (Luvox), guanethidine, insulin, MAO inhibitors [phenelzine (Nardil) and tranylcypromine (Parnate)] even if you stopped taking them within the past 2 weeks, medications for weight loss and depression, paroxetine (Paxil), sertraline (Zoloft),and vitamins.
* tell your doctor if you have or have ever had heart disease, high blood pressure, arteriosclerosis (narrowing of the arteries), hyperthyroidism (overactive thyroid gland), diabetes, glaucoma, or a history of drug abuse.
* tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking phentermine, call your doctor.
* you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
* remember that alcohol can add to the drowsiness caused by this drug.
* if you have diabetes, you may need a larger dose of insulin while taking phentermine. Call your doctor if you have questions or problems.
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Side effectsGenerally, phentermine appears to be relatively well tolerated. It can produce side effects consistent with its catecholamine-releasing properties, e.g., tachycardia (increased heart rate) and elevated blood pressure, but the incidence and magnitude of these appear to be less than with the amphetamines. Because phentermine acts through sympathomimetic pathways, the drug may increase blood pressure and heart rate. It may also cause palpitations, restlessness, and insomnia. Additionally, phentermine has the potential to cause physical and psychological dependence.

More Common Symptoms

* Insomnia
* Increased blood pressure
* Irritability
* Nervousness
* Sense of well-being

Less Common to Rare Symptoms

* Blurred vision
* Change in sexual desire
* Clumsiness
* Confusion
* Diarrhea
* Dizziness
* Dry mouth
* Headache
* Irregular heartbeat
* Nausea or vomiting
* Psychosis
* Skin rash or itching
* Stomach pain
* Tiredness
* Unpleasant taste

Possible Overdose Symptoms

* Confusion
* Convulsions (seizures)
* Dizziness
* Fast Breathing
* Fever
* Hallucinations
* Hostility with urge to attack
* Irregular blood pressure
* Irregular heartbeat
* Lightheadedness or Fainting
* Mental Depression, following a period of excitement
* Tremors, Trembling, or Shaking
* Overactive Reflexes
* Panic
* Restlessness
* Severe nausea, vomiting or diarrhea
* Stomach cramps
* Tiredness or Weakness
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